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A simulated single-cell marker-gene expression dataset with 104 rows covering eight immune cell types and thirteen canonical marker genes. Each cell type strongly expresses its own marker genes (high average expression and percent expressed) and weakly expresses the rest, making it a realistic example for plotthis_DotPlotApp() where dot size encodes the percent of cells expressing a gene and dot fill encodes average expression.

Usage

example_markers

Format

A data frame with 104 rows and 4 columns:

cell_type

Immune cell type (factor: CD4 T, CD8 T, B, NK, Monocyte, Dendritic, Plasma, Platelet)

gene

Marker gene symbol (factor with 13 levels, e.g. CD3D, MS4A1, NKG7, LYZ, MZB1, PPBP)

avg_expression

Average expression of the gene in the cell type

pct_expressed

Percent of cells in the cell type expressing the gene

Source

Simulated in data-raw/generate_example_data.R.

Author

Jacob Martin