A dataset containing differential expression results from comparing treated vs untreated samples in the airway dataset using limma-voom.
Format
A data frame with columns:
- logFC
Log2 fold change between treated and untreated conditions
- AveExpr
Average log2 expression
- t
Moderated t statistic
- P.Value
Moderated t-test p-value
- adj.P.Val
Benjamini-Hochberg adjusted p-value
- B
Log-odds of differential expression
- ensembl
Ensembl gene ID
- symbol
Gene symbol
Source
Generated from the airway Bioconductor package using limma.
The contrast compares dexamethasone treatment ("trt") vs untreated ("untrt").
Examples
library(VizModules)
head(airway_voom)
#> logFC AveExpr t P.Value adj.P.Val B
#> ENSG00000134686 1.381139 6.839533 17.35671 3.800818e-08 0.0001823477 9.401640
#> ENSG00000152583 4.574855 4.167526 18.56584 2.123270e-08 0.0001823477 9.236394
#> ENSG00000125148 2.198075 7.024695 16.55131 5.724844e-08 0.0001823477 9.010762
#> ENSG00000148175 1.440288 8.856653 16.69282 5.320156e-08 0.0001823477 8.916373
#> ENSG00000179094 3.185870 4.421045 16.64713 5.447236e-08 0.0001823477 8.867509
#> ENSG00000120129 2.952724 6.645078 15.89011 8.128610e-08 0.0002157604 8.691210
#> ensembl symbol
#> ENSG00000134686 ENSG00000134686 PHC2
#> ENSG00000152583 ENSG00000152583 SPARCL1
#> ENSG00000125148 ENSG00000125148 MT2A
#> ENSG00000148175 ENSG00000148175 STOM
#> ENSG00000179094 ENSG00000179094 PER1
#> ENSG00000120129 ENSG00000120129 DUSP1